For EPIC users, please direct providers to Order Set "Contrast Allergy Pre Treatment"
PREMEDICATION FOR CONTRAST REACTION ORAL REGIMEN (Preferred to IV premedication, unless immediately urgent): - 50 mg PO Prednisone (13, 7, and 1 hour (s) prior to contrast administration) AND 50 mg PO Diphenyhydramine (Benadryl®) 1 hour prior - 32 mg PO Methylprednisolone 12 and 2 hours prior to contrast administration AND 50 mg PO Diphenyhydramine 1 hour prior INTRAVENOUS PREMEDICATION (Emergency): - 200 mg of IV Hydrocortisone (Q4H until scan, ideally 2 doses) AND 50 mg IV Diphenhydramine 1 hour prior NOTES: - Steroids must be given 4 -6 hours pre contrast to be effective - Pre-medication may help reduce, but not fully eliminate, the risk of a serious contrast reaction in a patient considered to be at elevated risk. It mostly reduces chance of minor risks. |
